Colloidal Silver – What You Need to Know

June 29th, 2015 by Loretta Lanphier, NP, BCTN, CN, CH, HHP

Colloidal Silver – What You Need to Know

The mention of colloidal silver as being an effective substitute for or in addition to faltering-antibiotics tends to cause various reactions. Most of us have probably read that colloidal silver is not effective and downright dangerous. On the other hand, those who have personally experienced what an effective colloidal silver can do sing its praises. So which is it? Is colloidal silver dangerous, ineffective, snake-oil or is it something that deserves our attention because of its potential health benefits? Let’s talk about colloidal silver – what you need to know.

History of Colloidal Silver

Silver has long been recognized in recorded history as having germicidal properties. In 69 B.C. silver nitrate was described in the contemporary pharmacopoeia. In ancient Greece, Rome, Phoenecia and Macedonia, silver was used extensively to manage many immune challenges. From the time man first learned to work with silver, he has known that it delayed the spoilage of foods and that it reduced the symptoms of illness. Hippocrates, the “Father of Medicine,” used silver and instructed that it promoted tissue repair and was a notable topical aid. In the days before refrigeration, people tossed a silver coin in a bucket of milk to keep it from spoiling. Chemists put silver dimes in Petri dishes to sterilize them.

Dr. Carl Credé (1819-1892), a French surgeon, was the first to talk about the benefits of using silver nitrate to reduce newborn’s eye infections. He was also among the first surgeons to use silver nitrate in the prevention of wound infections.

By the late 1800s the recognition that silver was lethal to bacteria in relatively low concentrations was common medical knowledge. Between 1900 and 1940 silver was the primary antibiotic used in medical practice. More than 96 different silver medicinals (many used intravenously) were in use prior to 1939, as documented by The Council on Pharmacy and Chemistry of the American Medical Association.  Physicians mixed their own silver preparations in their offices which were given orally or injected. However, the shelf life was poor, as they had no way to keep the silver particles in suspension for longer than fifteen minutes.

The use of silver as an antibiotic gave way to the convenience of sulfa drugs and then eventually to the use of penicillin. These drugs, at that time, seemed more effective and were, of course, easier to use. However, with this convenience there would be an eventual price to pay. We are now experiencing antibiotic-resistant strains from overuse of these convenient drugs. And we now must often use highly toxic doses of antibiotics to get a result in the bacteria that can still be killed by antibiotics, a deep concern of antibiotic-related toxicity to the humans consuming them. It is important to note that bacteria do not generally develop resistance to silver unless the bacteria has a very thick wall that does not absorb it. Colloidal silver is effective against most gram positive and gram negative bacteria.

ACS200 Extra Strength Silver

How Colloidal Silver Works

Silver ions bind to cell walls and are then absorbed into the single-cell bacteria or fungus where they interfere with the cellular energy production and kill the organism. The fermentation system of energy production used by these single cell organisms is different than the aerobic energy producing system of human cells, which are not so affected by silver. This shows that silver is not toxic to human cells.

“We’ve reached the end of antibiotics, period… We’re here. We’re in the post-antibiotic era. There are patients for whom we have no therapy, and we are literally in a position of having a patient in a bed who has an infection, something that five years ago even we could have treated, but now we can’t.”
Dr. Arjun Srinivasan, associate director, The Centers for Disease Control & Prevention

Reasons to Use Colloidal Silver

  • New research shows that low doses of silver can massively boost the effect of antibiotics on bacteria, making them up to 1,000 times more sensitive to the drugs. The researchers hope their discovery will give new life to old antibiotics, including those to which microbes have become resistant.
  • Drug-resistant super-bug infections have reached near-epidemic levels across U.S. hospitals, with an alarming 500% increase now documented in a study just published in the August issue of Infection Control and Hospital Epidemiology (the journal of the Society for Healthcare Epidemiology of America).
  • Silver has been used for centuries to boost the immune system.
  • Many consider colloidal silver an antiseptic more than an antibiotic since it kills more than bacteria; it can destroy viruses and eliminate fungal infections.
  • Bacteria that are resistant to silver haven’t developed, while colloidal silver can destroy antibiotic-resistant pathogens, even MRSA.
  • Conventional medicine suggests adding colloidal silver to antibiotics to stop the super-bug strains that have developed immunity to those antibiotics.
  • Unlike prescription antibiotic drugs, silver does not create resistance or immunity in pathogens killed by it.

“Taken internally, colloidal silver can be used to fight infection. It has been shown to be effective against more than 650 disease-causing organisms, including Escherichia coli (E. coli) bacteria and the
fungus Candida albicans.”
Dr. James F. Balch & Phyllis A. Balch, CNC

Side Effects of Colloidal Silver

Even though the National Center for Complimentary and Integrative Health reports that colloidal silver may cause poor absorption of some drugs, there is very limited research proving that side effects to colloidal silver use even exist.

Warnings about colloidal silver causing an irreversible condition called argyria (when people turn blue) are rampant on the Internet. However, it is important to understand that this argyria is caused by misuse not of true colloidal silver, but by cheaper products marketed as colloidal silver. Colloidal silver produced with high voltage technology does not cause the side effects that can occur with the ingestion of large silver salts or silver particles. A good colloidal silver product will also have third-party product research backing up any claims. Make sure the colloidal silver that you use does not contain any additional ingredients such as salts or proteins. These ingredients provide an unstable solution. Because there are so many different types of colloidal silver on the market, I definitely recommend that you do your own research about any colloidal silver product you are considering to purchase.

Because colloidal silver is such a potent antibacterial agent, it is advisable to supplement with probiotics during use even though there is no current proof that a properly made colloidal silver will harm gut flora.

latero-flora probiotic

Recent Research on Colloidal Silver

Over the past few years, several new studies have demonstrated the fact that silver is one of the most effective agents in the battle against MRSA and other deadly antibiotic-resistant super pathogens, including the:

Brigham-Young Clinical Study – This study, published in the journal Current Science in 2006, found that a number of the antibiotic drugs which had previously been able to kill MDR (multiple drug-resistant) pathogens, such as MRSA, could be restored to full efficacy against the deadly pathogens, but only if a liquid silver solution similar to colloidal silver was used in conjunction with the drug.

Iranian Clinical Study – This study also found that silver increases the effectiveness of antibiotic drugs against staph infections. The researchers concluded:

“The antibacterial activities of penicillin G, amoxicillin, erythromycin, clindamycin, and vancomycin were increased in the presence of silver nano-particles (Ag-NPs) against both test strains. The highest enhancing effects were observed for vancomycin, amoxicillin, and penicillin G against S. aureus.”

Taiwanese Clinical Study – Published in the journal Colloids Surface B Biointerfaces in 2007, this study demonstrated that colloidal silver, by itself, eradicates both MRSA and Pseudomonas aeruginosa, another deadly and extremely opportunistic superbug.

Czech Clinical Study – Likewise, this Czech study published in the prestigious Journal of Physical Chemistry B in 2006, also demonstrated that colloidal silver was a highly effective agent against MRSA:

“…silver particles with a narrow size distribution with an average size of 25 nm, which showed high antimicrobial and bactericidal activity against Gram-positive and Gram-negative bacteria, including highly multi-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). The study further demonstrated that very low concentrations of silver could be utilized to destroy MRSA, as long as the silver particles were very small, averaging 25 nm.”

More Colloidal Silver Studies

Colloidal Silver Kills Antibiotic-Resistant Staph, E. coli, Pseudomonas and Salmonella

In this clinical study, titled “Colloidal Silver as a New Antimicrobial Agent,” published in the respected International Journal of Microbiological Research in 2010, the researchers demonstrated that colloidal silver effectively decimated antibiotic-resistant strains of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi. The researchers concluded, “Resistant clinical isolates of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi were used as the test organisms. This study demonstrated powerful antimicrobial activity of colloidal silver against all multidrug-resistant clinical pathogens tested.”

Colloidal Silver Kills up to 99.7% of Six Multidrug-resistant Superbugs

In this fascinating clinical study published in the World Journal of Microbiology and Biotechnology in 2010, it was found that antimicrobial silver killed up to 99.7% of drug-resistant bacteria, including some of the most virulent multidrug-resistant strains. The study authors stated: “In our study, antimicrobial silver nanoparticles exerted a bactericidal effect against six drug-resistant bacterial strains…the same nanosilver concentrate inhibited 99.7% of erythromycin-resistant Streptococcus pyogenes, 95.7% of ampicillin-resistantE. coli and 92.8% of multidrug-resistant P. aeruginosa.” The researchers further concluded that silver exhibited bactericidal effect rather than merely bacteriostatic effect. That’s important news, because it means the use of antimicrobial silver is so effective against drug-resistant strains, it outright kills them rather than merely inhibiting their growth!

Colloidal Silver Kills 49 Different Strains of Antibiotic-Resistant Superbugs!

In this clinical study conducted by researchers at the Department of Pathology at West Virginia University, and published in the International Wound Journal in October 2012, a total of 49 different antibiotic-resistant bacteria were isolated from burn wounds and tested against silver. These deadly, pathogens included Vancomycin-resistant Enterococcus faecium, Methicillin-resistantStaphylococcus aureus, multidrug-resistant Pseudomonas aeruginosa, multidrug-resistant Vibrio sp, drug-resistantKlebsiella pneumonia, drug-resistant Escherichia coli, multidrug-resistant Acinetobacterbaumannii and 42 others. After exposing these drug-resistant pathogens to antimicrobial silver the researchers concluded, “…all forty-nine antibiotic-resistant bacteria showed susceptibility to the antimicrobial activity of silver…”

Colloidal Silver and Harmful Organisms

A 2013 study of silver nanoparticles, the ones used in true colloidal silver products, was performed to look at the effect of silver against a variety of microorganisms. The researchers found a notable effect against common disease-causing bacteria. Researchers from around the world are also testing silver nanoparticles for use in dental procedures. One particular study found that silver nanoparticles helped prevent infection during root canals.

An Australian research team tested silver nanoparticles against bacteria known to intensify rheumatoid arthritis. This particular study used a silver preparation in a human participant who currently suffered from rheumatoid arthritis. The researchers found it was potent and, best of all, offered long-lasting protection against irritation associated with the bacteria.

As soon as a silver atom encounters a bacterial organism, it binds to the cell and the silver is absorbed through the cell wall. Once inside the organism, the silver halts certain required metabolic functions. This supposedly kills the harmful organism. It’s very important to understand that silver does this to bacteria and other harmful organisms; however it does not have this same effect on healthy human cells.

READ Colloidal Silver – Experts Speak

In Conclusion…

Always do your research and/or speak with a knowledgeable healthcare professional. Taking recommended doses of true colloidal silver — professionally produced by a reputable healthcare company — comes with a risk that is essentially zero.


Bacteria Do Not Develop Resistance to Silver. J Wound Care.  Lansdown AB.

Lansdown AB. Silver in health care: antimicrobial effects and safety in use. Curr Probl Dermatol. 2006 October 33:17-34. Imperial College Faculty of Medicine, Charing Cross Hospital, London, UK

Kim Y, Suh HS, Cha HJ, Kim SH, Jeong KS, Kim DH. Argyria from Excessive Colloidal Silver Intake. Am J Ind Med.

Brandt D, Park B, Hoang M, Jacobe HT. Argyria Caused by Homemade Silver Solution. J Am Acad Dermatol.

How Silver Kills Bacteria. Br J Nurs.  Lansdown AB.

Colloidal Silver Inhibts Smallpox Virus. Pharmaceutical Chemistry Journal N. E. Bogdanchikova, A. V. Kurbatov, V. V. Tretyakov, and P. P. Rodionov.

Cases of Drug Resistant Super Bug Significantly Rise in South Eastern U.S. Science Daily, 2014.

Current Science, October 2006;91(7) (PDF)

Nanomedicine: Nanotechnology, Biology and Medicine, June 2007;3(2):168-171

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The Journal of Physical Chemistry B, August 2006;110(33):16248-53 

J. Wesley Alexander. History of the Medical Use of Silver. Surgical Infections. June 2009, 10(3): 289-292. doi:10.1089/sur.2008.9941

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Lansdown AB. A review of the use of silver in wound care: facts and fallacies. Br J Nurs. 2004 Mar;13(6 Suppl):S6-19.

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Pokrowiecki R1, Zareba T2, Mielczarek A3, Opaliska A4, Wojnarowicz J4, Majkowski M5, Lojkowski W4, Tyski S2. Evaluation of biocidal properties of silver nanoparticles against cariogenic bacteria. Med Dosw Mikrobiol. 2013;65(3):197-206.

Felipe Solsona, Juan Pablo Mendez. Water Disinfection. Pan American Center for Sanitary Engineering and Environmental Sciences. 2003.

Abbaszadegan A1, Nabavizadeh M, Gholami A, et al. Positively charged imidazolium-based ionic liquid-protected silver nanoparticles: a promising disinfectant in root canal treatment. Int Endod J. 2014 Sep 2. doi: 10.1111/iej.12377.

Disaanayake DM1, Faoagali J, Laroo H, Hancock G, Whitehouse M.. Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis. Inflammopharmacology. 2014 Apr;22(2):73-7. doi: 10.1007/s10787-013-0198-0.

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Loretta Lanphier is a Naturopathic Practitioner (Traditional), Certified Clinical Nutritionist, Holistic Health Practitioner and Certified Clinical Herbalist as well as the CEO / Founder of Oasis Advanced Wellness in The Woodlands TX. She has studied and performed extensive research in health science, natural hormone balancing, anti-aging techniques, nutrition, natural medicine, weight loss, herbal remedies, non-toxic cancer support and is actively involved in researching new natural health protocols and products.  A 14 year stage 3 colon cancer survivor, Loretta is able to relate to both-sides-of-the-health-coin as patient and practitioner when it comes to health and wellness. “My passion is counseling others about what it takes to keep the whole body healthy using natural and non-toxic methods.” Read Loretta’s health testimony Cancer: The Path to Healing. Loretta is Contributor and Editor of the worldwide E-newsletter Advanced Health & Wellness
†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. Oasis Advanced Wellness/OAWHealth does not dispense medical advice, prescribe, or diagnose illness. The views and nutritional advice expressed by Oasis Advanced Wellness/OAWHealth are not intended to be a substitute for conventional medical service. If you have a severe medical condition or health concern, see your physician of choice.










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